陈龙现
杭州师范大学基础医学院讲师
个人简介：
博士毕业于中国科学院分子植物科学卓越创新中心，主要研究方向为RNA编码及A-to-I RNA编辑等。已发表SCI研究论文10余篇，其中以第一作者（含共同）身份在Genome Biology, Molecular Plant, Journal of Experimental & Clinical Cancer Research, BMC Genomics等期刊发表论文。2024年3月入职杭州师范大学基础医学院免疫与病原生物学系。
教育经历：
2024 – 至今 杭州师范大学基础医学院 讲师
2021 – 2023 浙江大学生命科学研究院 博士后
2014 – 2021 中国科学院上海分子植物科学卓越创新中心 博士
2008 – 2012 烟台大学 学士
研究方向：
RNA编辑与病毒免疫
电子邮箱：
lxchen@hznu.edu.cn
学术成果：
1.Chen L, Ou L, Jing X, Kong Y, Xie B, Zhang N, Shi H, Qin H, Li X, Hao P: DeepEdit: single-molecule detection and phasing of A-to-I RNA editing events using nanopore direct RNA sequencing. Genome Biol 2023, 24:75.
2.Lin JL, Chen L, Wu WK, Guo XX, Yu CH, Xu M, Nie GB, Dun JL, Li Y, Xu B, et al: Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells. Mol Plant 2023, 16:1990-2003.
3.Tu X, Chen L, Zheng Y, Mu C, Zhang Z, Wang F, Ren Y, Duan Y, Zhang H, Tong Z, et al: S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function. Journal of Experimental & Clinical Cancer Research 2024, 43:72.
4.Zhu Y, Chen L, Hong X, Shi H, Li X: Revealing the novel complexity of plant long non-coding RNA by strand-specific and whole transcriptome sequencing for evolutionarily representative plant species. BMC Genomics 2022, 23:1-16.
5.Zhu Y, Chen L, Zhang C, Hao P, Jing X, Li X: Global transcriptome analysis reveals extensive gene remodeling, alternative splicing and differential transcription profiles in non-seed vascular plant Selaginella moellendorffii. BMC Genomics 2017, 18:1042.
6.Jing X, Xie B, Chen L, Zhang N, Jiang Y, Qin H, Wang H, Hao P, Yang S, Li X: Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing. Nucleic Acids Res 2018, 46:e90.
7.Kong Y, Zhou H, Yu Y, Chen L, Hao P, Li X: The evolutionary landscape of intergenic trans-splicing events in insects. Nat Commun 2015, 6:8734.
8.Yu Y, Zhou H, Kong Y, Pan B, Chen L, Wang H, Hao P, Li X: The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection. PLoS Genet 2016, 12:e1006191.
9.Qin H, Ou L, Gao J, Chen L, Wang J-W, Hao P, Li X: DENA: training an authentic neural network model using Nanopore sequencing data of Arabidopsis transcripts for detection and quantification of N6-methyladenosine on RNA. Genome Biol 2022, 23:25.
10.Kong Y, Xu P, Jing X, Chen L, Li L, Li X: Decipher the ancestry of the plant-specific LBD gene family. BMC Genomics 2017, 18:1-10.
11.Li X, Zhou H, Xiao N, Wu X, Shan Y, Chen L, Wang C, Wang Z, Huang J, Li A, Li X: Expanding the Coverage of Metabolic Landscape in Cultivated Rice with Integrated Computational Approaches. Genomics Proteomics Bioinformatics 2022, 20:702-714.
